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KMID : 0978920060070020215
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Korean Journal of Clinical Geriatrics
2006 Volume.7 No. 2 p.215 ~ p.224
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The Prediction of the Biological Age Using Clinical Parameters
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Bae Chul-Young
Kang Young-Gon
Kim Se-Hyun
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Abstract
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Background: Biological age is the objective assessment of a person’s health status and may be used to investigate individual variation of organs and functions during aging. To determine biological age in clinical practice settings, we developed models for predicting biological age of individuals by employing all parameters of physical, biochemical, and hormonal characteristics.
Methods: This was a community based cross-sectional study. Subjects were recruited from the health promotion center at one community hospital in Korea from 1999 to 2003. Among these, data obtained from the 3,575 participants (1,302 men and 2,273 women) was used for clinical evaluation and statistical analysis. For our test battery we selected twenty-five parameters among the routine tests that are conducted in annual health check-ups.
Results: For males, the best models were developed using 15-, 7-, 5-, 4- of the 25 chosen parameters for total, physical, biochemical and hormonal characteristics, respectively (R2’s= 0.62, 0.38, 0.33, 0.36). Similar to males, for the females, 14-, 6-, 8-, 3-paramaters were developed as the models for total, physical, biochemical, and hormonal characteristics, respectively (R2’s= 0.66, 0.40, 0.42, 0.37).
Conclusion: Our biological age prediction models may be useful as supplementary tools in the evaluation of aging and health status. A profile of physical, biochemical, and hormonal parameters selected in the prediction model are feasible to be used in annual health check-up or in the clinical practice.
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KEYWORD
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Biological age, Chronological age, Evaluation of aging
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